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Thursday, November 13, 2008

Drug Facts

Before they drug you!

8 comments:

  1. You make a good point.

    I'm actually looking for some drug facts, for a friend, of course.

    My friend has found him/herself in possession of some Fentanyl patches. They are 72 hour Mylan transdermals in the 75, 50 and 25 mcg/hr sizes. My friend enjoys chemical entertainment, but he/she doesn't have many 72 hour periods set aside for euphoria.

    My friend wants to know if anyone knows of an efficient and safe way of delivering this product for a short period, say 6 to 8 hours.

    ReplyDelete
  2. Woody, according to Wikipedia, "Fentanyl patches are manufactured in five patch sizes: 12.5 micrograms/hour, 25 µg/h, 50 µg/h, 75 µg/h, and 100 µg/h. Dosage is based on the size of the patch, since the transdermal absorption rate is generally constant at a constant skin temperature. Rate of absorption is dependent on a number of factors. Body temperature, skin type, amount of body fat, and placement of the patch can have major effects. The different delivery systems used by different makers will also affect individual rates of absorption. The typical patch will take effect under normal circumstances usually within 8-12 hours,"

    Aside from issues of placement, body fat and the like, as the dosage from a single patch is relatively constant, one wonders whether your friend might consider slapping a few patches at the same time - having another friend ready to help remove them after an agreed upon time or set of reactions are manifested?

    ReplyDelete
  3. TT, thanks for your advice, but my friend is risk averse.

    Death is to be avoided.

    My thinking is that it would be wise to cut the patch (these do not appear to be gel filled) and apply reduced dose during the late afternoon, with reasonable certainty that there no need to drive during the evening. The effects should kick in during or soon after dinner. Necessary props would be music, wine and fluffy pillows. My friend has no experience, and does not know if cutting a patch is safe or if this approach is reasonable.

    ReplyDelete
  4. Good luck to your "friend"!

    ReplyDelete
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